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Relying solely on a single pathway limits a providers ability to treat complex metabolic resistance
The comparator groups differed among studies, with some employing placebo controls (e.g., PIONEER-6, Gerstein 2019), others using active comparators such as sitagliptin, glimepiride, DPP-4 inhibitors, or SGLT2 inhibitors, and some utilizing standard care or intensive lifestyle interventions as the control
The injectable Wegovy helps people lose an average of 15% to 16% of their body weight
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The need for ongoing treatment often surprises people who view obesity as a problem to be solved rather than a chronic condition to be managed
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