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Our study is observational and these results should therefore be replicated in a randomised controlled trial to confirm and extend our findings, said Dr Max Taquet, Clinical Lecturer at the University of Oxford and senior author of the study
What the evidence does show: a sustained national decline in adult obesity over four years, running concurrently with a dramatic increase in GLP-1 prescriptions a pattern that public health researchers say is consistent with the drugs' documented clinical efficacy
If you use oral contraceptives, consider using a non-oral method or adding a barrier method for 4 weeks after starting tirzepatide and after each dose escalation
There is early postoperative surges in GLP-1 and GIP levels, decline over time and may contribute to weight regain (WR)
It remains in clinical trials (Phase 3 studies are underway) and will require FDA approval before it can be prescribed
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