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Either way, the trajectory since 1992 has a shape worth noting

Side effects are usually mild and temporary

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However, without a balanced diet and exercise, that number may drop to just 2 to 4 pounds per monthfar less than the 10+ pounds some achieve with the right approach

The SURMOUNT-1 trial (N=2,539), published in the New England Journal of Medicine in 2022 (DOI: 10.1056/NEJMoa2206038), evaluated tirzepatide at 5mg, 10mg, and 15mg weekly doses versus placebo in adults with obesity or overweight