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Obesity: Excess body fat, especially abdominal fat, increases insulin resistance and impairs the ability of cells to use insulin effectively, and leads to elevated blood sugar levels

It was 2 shots and

Figure 4, Panel C, presents a forest plot of HRs for all-cause mortality, illustrating a numerically lower point estimate for tirzepatide compared to the GLP-1RA class

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The technology is promising, but it is still in the research phase