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The peptide enhances neutrophil chemotaxis while simultaneously promoting their apoptosis and clearance by macrophages, preventing the chronic inflammation that impairs healing

Reviews of retro-inverso peptides describe this design as a peptide chemistry strategy often studied for stability and molecular recognition questions [5]

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Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed