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Diniz CRAF, Crestani AP (2023) The times they are a-changin: a proposal on how brain flexibility goes beyond the obvious to include the concepts of upward and downward to neuroplasticity

Patients describe it as: I process information very slowly my brain stalls after every thought it takes forever to process simple tasks everything feels muffled I lose words mid-sentence my thinking feels cloudy and sluggish I feel intoxicated even though I dont drink This level of fog can: damage your performance at work or school strain relationships undermine confidence make everyday decisions feel exhausting It affects your work, relationships, and sense of self

These slow-cycling resistant cells expressed drug resistance and CSC markers (ABCG2, CD44, CD105) and exhibited a low OXPHOS-glycolysis signature

Without one, the comparison becomes meaningless

It usually takes 3-5 working days