Though compounded semaglutide, for example, contains the same active ingredient as Wegovy, the Food and Drug Administration doesnt verify the safety, quality, or effectiveness of such mixed or altered meds
The following groups should avoid or exercise extreme caution: Pregnant or breastfeeding women Individuals with active cancers People with uncontrolled diabetes Those with severe cardiovascular conditions Individuals with pre-existing hormonal imbalances A medical consultation is MANDATORY before starting treatment, especially if you have any pre-existing conditions or concerns about your eligibility
Off-label use means a medicine is prescribed outside its main licensed indication, based on clinical judgement
TRIUMPH-1, the main obesity trial, required a BMI of 30 kg/m or higher, or 27 or higher with a weight-related condition such as hypertension, dyslipidemia, sleep apnea, or cardiovascular disease
Nutr Diabetes (2012) 2:e544