TB-500 is a fragment of thymosin beta-4, a naturally occurring peptide found throughout the body
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However, its important to note that 24 weeks, while substantial for clinical trials, represents a relatively limited timeframe for assessing lifetime exposure safety
Studies also noticed that pycnogenol supplementation proved as a potent antioxidant which enhanced tFAM, Mn-SOD, reduced GSH, catalase and mitochondrial biogenesis [31,32]
Therefore, in this case, the total amount of drug absorbed and eliminated from the body may not be significantly different compared to healthy individuals