Pre-treatment of cells with these incretin-based drugs followed by 48 h treatment with 1 M doxorubicin increased doxorubicin sensitivity as observed by a decrease in viability by MTT assay
Participants gave informed consent to participate in the study before taking part and were made aware of the study objectives and the aim for publication of a manuscript
In studies involving inflammatory bowel disease (IBD), the peptide has been shown to mitigate intestinal inflammation, reduce lesion size, and promote the regeneration of the epithelial lining
Recent studies have indicated that excess Fe 2+ can donate electrons to hydrogen peroxide (H 2 O 2 ) to generate hydroxyl radicals, which have high reactivity with biological molecules, such as proteins, lipids, and nucleic acids, leading to lipid peroxidation and the eventual development of ferroptosis ( 2+ is also involved in the catalytic subunit of lipoxygenase (ALOX)
It is a hormone your body produces naturally