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Accordingly, meta-analyses found that the risk of MACE was lower among the GLP-1 RA group than among the control group, estimating a risk reduction between 12 and 14% (Zhu et al., 2020
Research Insight: The SURMOUNT-5 trial, a phase 3b study, demonstrated that participants treated with tirzepatide experienced a superior percentage change in body weight and waist circumference compared to those treated with semaglutide over 72 weeks
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