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Autophagy 17 , 43234340 (2021)

Effect of Iodine Restriction on Thyroid Function in Patients with Primary Hypothyroidism

Thats because it breaks down in the gastrointestinal tract

Dosage : Higher doses might increase the amount absorbed but also risk more degradation

Toxicokinetic analysis revealed that rotigotine behenate-PLGA exhibited sustained release, where Cmax and AUC 0 28 d increased proportionally with the dose with moderate accumulation of rotigotine