This attests to an overall unchanged bioavailability of the COCs when given with a GLP1 analogue
Pharmacokinetic sampling for metformin was performed from pre-dose to 30 h post-dose (after the last of seven doses administered over 3.5 days)
Kosiborod MN, Deanfield J, Pratley R, et al
However, its effects on digestion can vary from person to person, so it is important to monitor bowel health while using the medication
In this metabolomic profiling study, 13 long-chain acylcarnitines were analyzed which included 6 saturated (C14, C16, C18, C14OH, C16OH, and C18OH), 5 monounsaturated (C14:1, C16:1, C18:1, C16:1OH, and C18:1OH), and 2 polyunsaturated (C14:2 and C18:2) acylcarnitines