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Gastrointestinal discomfort, including mild nausea or stomach upset, has been noted in anecdotal accounts, though no severe gastrointestinal effects have been documented in controlled studies

The main precursors of glutathione are glutamine , cysteine , and glycine , and there are supplements with these (and other) precursors

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They also found that vitamin C helps reprocess glutathione by converting oxidized glutathione back to its active form