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It can be fused to either the N -terminus or C -terminus of a protein

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Factors to consider when choosing your dosing time: Meal size and fat content: Take omega-3 with your largest, most fat-containing meal Medication schedule: Coordinate with other supplements or medications to improve adherence Side effect profile: If you experience reflux or nausea, consider which mealtime is best tolerated Personal routine: Choose a time you can maintain consistently to optimise long-term adherence Patients should discuss their dosing schedule with their healthcare provider, particularly if taking omega-3 for specific medical conditions or alongside other medications that may interact with fatty acid metabolism

doi: 10.1097/PRS.0000000000010631.