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SAR425899 was developed for the treatment of patients with T2D and obesity 11,12,13,14 aiming to lower glucose at least similar to marketed GLP-1 agonists, but with superior weight loss over GLP-1 receptor mono-agonists

Finally, the current experimental results are being used to with computational modeling to develop a machine learning algorithm to be used for prediction of theoretical CCS

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The cellular uptake of the nanoparticles in 143B cells was investigated upon labeling of NP4 with the well-characterized dye Cy5.5 into the nanoparticle formulation NP4-Cy5.5