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The impact on medication absorption diminishes over time as your body adapts, but those early weeks and dose adjustment periods carry the highest risk

The magnitude of IGF-1 increase varies by dose, duration, and individual responsiveness but is a reproducible finding across clinical practice and the smaller body of formal studies

Tsilou ET, Rubin BI, Reed GF, Iwata F, Gahl W, Kaiser-Kupfer MI (2002) Age-related prevalence of anterior segment complications in patients with infantile nephropathic cystinosis

Rates of other complicationsincluding wound dehiscence, infection, and rehospitalizationwere similar between the two groups

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