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They also contribute to substantial weight loss for people with obesity and show promise in helping to manage other conditions, such as cardiovascular disease and substance use disorder

There may be a number of sources of this oxidative stress, including mitochondrial superoxide production, ischemia-reperfusion mechanisms and auto-oxidation of catecholamines

[PubMed] Clarke R, Grimley Evans J, Schneede J, et al

Exenatide (Ex), a 39-amino-acid GLP-1 analogue peptide, is a potent agonist with high affinity for GLP-1Rs and has a significantly longer biological half-life than the exogenously administered GLP-1, which makes it an efficient treatment option in noninsulin-dependent diabetes mellitus [14,15,16,17]

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