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While there were no significant differences at baseline, a significant drug main effect was found, indicating that GLP-1 concentrations were lower during cannabis administration sessions (oral, smoked, and vaporized), compared to the placebo condition (Fig

After 12 months of use, 58% of patients achieved a BMI reduction 5%, 35% achieved a BMI reduction 10%, and 17% achieved a BMI reduction 15%

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In addition to lowering blood sugar levels through these mechanisms, GLP-1 slows down stomach emptying