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However, some individuals may experience initial gastrointestinal side effects when starting berberine

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In conclusion, our findings suggest that co-administration of L-carnitine and synbiotic may be an encouraging therapeutic strategy for obesity and related cardiometabolic complications, possibly due to simultaneous targeting of multiple metabolic pathways, augmenting their bioavailability/function through potential complementary or synergistic mechanisms

Other DPP4 inhibitors were not included in this meta-analysis