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54 The phase 3 randomised controlled Study of Retratrutide in Participants with Obesity and Cardiovascular Disease (TRIUMPH-3) seeks to determine the percentage change from baseline in body weight in patients with BMI 35 kg/m 2 and established CVD (clinical trial number NCT05882045
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Animal studies reveal doxorubicin administration causes dramatic weight loss and liver damage, evidenced by elevated plasma aspartate aminotransferase (AST) levels, an established marker of hepatotoxicity
Practitioners report that most patients are willing to continue if they perceive any benefit
