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In general, consistent with preclinical studies, RSV supplementation (500 mg/day, P.O for 4 weeks) raised erythrocyte PPAR- and Sirt1 expression and serum TAC and attenuated the total/HDL cholesterol ratio in CHD patients with type 2 diabetes [198]

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Originally FDA-approved for reducing excess abdominal fat in HIV patients with lipodystrophy, Tesamorelin has gained significant attention for its body composition benefits in the general population