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Long-term use of medications like antacids, proton-pump inhibitors, H2 blockers, or metformin
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There are many different types of vitamin B12 available, including: cyanocobalamin methylcobalamin adenosylcobalamin hydroxycobalamin While cyanocobalamin is the Vitamin B12 supplements are available in a wide range of doses as well, including high dose supplements with 1,000 mcg to 2,000 mcg per serving