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This sounds beneficial but introduces unpredictability: the same oral dose could produce significantly higher plasma levels than intended, and the effect varies depending on the potency and half-life of the inhibitor
LIR is suitable to be administered once a day, with a t max of 9~13 hours and t 1/2 of 13 hours (8082)
Thus, rapid depolymerization for phase I is followed by a requirement for actin polymerization to facilitate sustained ISG release in phase II
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