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From the experimental results of example 1 and comparative examples 1 and 2, it can be seen that: the invention takes 7 th-8 th amino acid of a Cagrilintide sequence as pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, takes 10 th-11 th amino acid of the Cagrilintide sequence as pseudo-pro dipeptide Fmoc-Ala-Thr (pro-me-me) -OH, takes 21 st-22 th amino acid of the Cagrilintide sequence as pseudo-pro dipeptide Fmoc-Ser-Ser (pro-me-me) -OH, and has synergistic effect on improving the purity and yield of Cagrilintide

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