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People with certain health issues should not take them

Regulatory Status MT-II : Not approved for tanning or sexual function Afamelanotide (MT-I) is approved for EPP (EU 2014

2.3 Discontinuation for Iodinated Contrast Imaging Procedures Discontinue JANUMET XR at the time of, or prior to, an iodinated contrast imaging procedure in patients with an eGFR between 30 and 60 mL/min/1.73 m2