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S-Adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via camp/protein kinase a pathway

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Even the recommended dose of 4 g/day for two weeks can elevate liver enzymes like ALT to three times the normal limit in about one-third of patients 59

doi:10.1128/msphere.00474-22 92