It is best to take it with carbohydrates to significantly increase absorption
Retatrutide's bioavailability via subcutaneous injection is approximately 95% per Phase 1 pharmacokinetic data (Coskun et al., 2022), meaning very little drug is lost at the injection site regardless of which approved location you choose
Sierra-Johnson J, Romero-Corral A, Somers VK, Lopez-Jimenez F, Mlarstig A, Brismar K, Hamsten A, Fisher RM, Hellnius M-L
However, it is always best to consult with your healthcare provider to determine the right schedule for your specific needs, especially if you have existing health concerns
Higher doses (1000mg+) do not proportionally increase plasma glutathione levels due to absorption saturation