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There are some very rare side effects listed in medical literature (mostly when large doses are given): for example, one out of many thousands of patients might develop a disturbance in liver enzymes or a tingling in the fingers or toes

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In clinical trials of semaglutide injection for weight management, cholelithiasis was reported in 1.6% of semaglutide-treated patients compared with 0.7% of placebo-treated patients