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Similar to ischemia-reperfusion, intense exercise creates a scenario for certain active muscle fibers that can lead to transient or prolonged episodes of hypoxia followed by reoxygenation at the cessation of exercise

Svetkey, L

Reversed-phase HPLC analysis requires wider-pore stationary phases 300 angstrom C18 or C4 columns and shallower acetonitrile gradients compared to unmodified peptides