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Kaufman, H

Miller, T

The discovery of GLP-1R/GcgR dual agonists has provided a fresh medicinal approach and renewed hope that obesity and its associated abnormalities might be managed with medicines as opposed to surgical interventions

These drugs helped lower blood sugar through a few specific mechanisms: Increased insulin secretion from the pancreas Reduced how much sugar the liver put into the bloodstream (via reducing glucagon) Slowed gastric emptying, which makes glucose appear slower in the blood stream

Medical devices and interventions such as nasogastric tubes, nasal cannulas, or recent nasal procedures may also increase the risk of epistaxis in patients who happen to be taking tirzepatide