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Pickart and colleagues (Nature, 1980, PMID 7453802) reported facilitated copper uptake into cultured cells, and Simon and colleagues (Life Sci, 2000, PMID 11045606) reported upregulated MMP-2 alongside its tissue inhibitors in fibroblast culture

The conversion of GSSG back to GSH during ROS production would explain the unbalanced activation of the glutathione oxidation/reduction cycle

But while generic versions could have been introduced in Canada earlier this year, so far, they havent appeared

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