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Semaglutide demonstrates substantial efficacy in clinical trials, whilst liraglutide produces moderate reductions

Administration routes tested included both intravenous injection and oral formulations delivered as capsules or tablets

Since apoptosis is defined by the NCCD as a caspase-dependent RCD [4], and considering the fact that eryptotic pathways dont culminate in activation of caspases [84], it has become clear that eryptosis is guided and executed alternatively

Notably, tirzepatide showed greater HbA1c reductions compared with other GLP-1 RAs, supported by high-certainty evidence