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Changes in the Nrf 2/Keap 1 ratio and PON1 concentration in plasma of patients undergoing the left main coronary artery stenting

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Others failed to properly monitor patients for signs of severe gastrointestinal injuries, pancreatitis, or vision loss

The Nrf2sMAF heterodimer binds to the antioxidant response element (ARE), which leads to the transcription of genes encoding antioxidant and detoxification enzymes such as SOD, CAT, GP X , heme oxygenase 1 (HO-1), NAD(P)H quinone dehydrogenase 1 (NQO1), which protect cells from oxidative stress and toxins (124126) (Figure 3)

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