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Quick Answer: Persistent hunger on semaglutide may occur due to insufficient time at therapeutic dose, hormonal adaptation during weight loss, dietary composition, medication interactions, or individual variation in GLP-1 receptor response

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Key Highlights GLP-1 and GIP are naturally occurring hormones that play a crucial role in regulating blood sugar levels and influencing metabolic health

doi:10.1016/j.ajog.2026.04.037 36.GLP-1 medicines for weight loss and diabetes: what you need to know