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5a) allows selective inhibition of CBS (raising cellular homocysteine levels and suppressing the production of H 2 S in a dose-dependent manner) over CSE

ROS can cause oxidative damage to lipid membranes by polyunsaturated fatty acids (PUFA), resulting in large amounts of lipid peroxides, which can lead to membrane damage and ferroptosis (ferroptosis) in intestinal epithelial cells (IECs) (4)

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c , Hydrogen-bond interactions between helices I and VII

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