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Astrocytes with low GSH may become less protective over time, releasing more inflammatory mediators and failing to supply an adequate amount of GSH and GSH precursors to neighboring neurons and microglia (Kwon et al., 2019
For the Zepbound OSA indication, Tricare references SURMOUNT-OSA, which showed AHI reduction of 27-30 events per hour over 52 weeks in patients with moderate-to-severe OSA and obesity
Kang R, Zhu S et al (2018) BECN1 is a new driver of ferroptosis
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