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Researchers should define the main question before selecting a model: whether the study is testing cytoprotection, migration, proliferation-associated endpoints, angiogenesis, extracellular matrix remodeling, endothelial signaling, or tissue-level recovery

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It has no effect unless the messages it generates reflect imaginary psychological values and are incorporated in complex symbologies of the social statuses at which the products are directed, regardless of their actual utilitarian value

daily for 1 week, once a week for 1 month, and then monthly for at least 6 months