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The dual-receptor mechanism produces a larger growth-hormone pulse, which translates to more noticeable changes in body composition, recovery, and sleep depth

But fewer studies have used gold-standard assessment techniques like DXA and indirect calorimetryto understand how GLP-1s affect: Lean mass Functional strength Risk of sarcopenia This matters clinically: lean mass loss does not always equal strength loss , but severe declines can impact mobility, metabolic health, and quality of life

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