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Butterfield, Methods Mol
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May reduce the impact of uncontrolled diabetes Long-term high blood sugar is associated with reduced amounts of Glutathione, leading to oxidative stress and tissue damage
HG also induced epithelial-mesenchymal transition (EMT) and upregulated fibrosis-related genes, suggesting that HG-induced EMT contributes to subretinal fibrosis, the end-stage of eye diseases, including proliferative DR
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