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As some examples, GLP-1RAs are safer and slightly more effective in improving glucose control, significantly reducing body weight, and preventing hypoglycemia than basal insulin in poorly controlled T2D with oral antihyperglycemic agents (61)

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Anumudu CK, Miri T, Onyeaka H (2024b) Multifunctional applications of lactic acid bacteria: enhancing safety, quality, and nutritional value in foods and fermented beverages

Phase II takes these highly reactive, dangerous intermediates and binds (conjugates) them to endogenous molecules to neutralize them