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Well-formulated low-carb/ ketogenic diets have proven effective: - reduce insulin/insulin resistance - reduce HbA1c - improve HDL - reduce triglycerides Ketons spare muscle, and may also benefit brain health (e.g., depression and anxiety)

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However, for injected B12, this distinction is less relevant because both forms enter circulation directly

In the coming years, integrating multi-omics approachesincluding transcriptomics, proteomics, metabolomics, and epigenomicswill deepen our understanding of the dynamic crosstalk between phytohormones and ROS during stress responses

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