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Down-regulation of a hepatic transporter multidrug resistance-associated protein 2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury

Importantly, asporin ( ASPN) and vascular cell adhesion molecule 1 ( VCAM1) were among the highly up-regulated genes

While it is often marketed as having superior systemic bioavailability, clinical data actually shows that ALCAR has a lower overall accumulation in blood plasma compared to LCT

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