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Additionally, while clinical guidelines for indicated use of GLP-1 RAs are rapidly changing as evidence for GLP-1 RA use evolves, the ethics of off-label use are particularly important to consider given the impact these shortages can have on access for patients who otherwise have a strong clinical indication to be on them
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2019;2020(432):p487493
Discontinuation In Phase 2, 6-16% of participants stopped because of adverse events versus 0% on placebo
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