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Preclinical and observational evidence, as well as some small studies, suggested potential benefits of GLP-1 agonists, but this large trial does not confirm clinical efficacy in early Alzheimers. Have the authors taken confounding factors into account
ICD-10 codes are special number codes used by doctors to define health issues such as weight loss
A further nuance sharpens what the trials actually showed
Tandem mass spectrometry identifies many mouse brain O -GlcNAcylated proteins including EGF domain-specific O -GlcNAc transferase targets
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