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In diabetes and obesity, growth factor-associated signaling in the brain deteriorates and energy use in the cerebral cortex decreases simultaneously with pro-inflammatory changes, while GLP-1RAs improve neuronal growth and repair, reduce inflammation and apoptosis, as well as oxidative stress [31]

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Its important to remember that GLP-1 is dose-dependent, meaning that many of the side effects are experienced by those taking larger doses of these prescription medications

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