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Moreover, severe or recurrent AKI often leads to abnormal repair of the kidney and renal fibrosis, accelerates renal function decline, and ultimately results in chronic kidney disease (CKD) and end-stage renal disease (ESRD) (Kaballo et al., 2017)
Biodistribution study The biodistribution of NP4 in orthotopic osteosarcoma mouse model was investigated using in vivo imaging system (IVIS)
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SHMT = serine hydroxymethyltransferase
Injections: Results can be seen within 1 to 3 months of treatment, with consistent weekly or bi-weekly injections
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