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13 C NMR (100 MHz, Chloroform-d) = 163.0, 162.5, 149.3, 146.8, 138.4, 125.7, 124.7, 115.0, 114.8, 65.6, 59.4, 32.0
Leveraging incretin biology for weight-loss remains popular, with ~35% of drug candidates exploiting this mechanism of action, (Figure 3 c)
Saviano A, Apta B, Tull S, Pezhman L, Fatima A, Sevim M
How Do You Read a Peptide COA
Components of the ER-associated degradation (ERAD) pathwayincluding Syvn1, Sel1l, Derl3, Amfr, and Ubxn4were also reduced, along with genes involved in vesicular trafficking (Sec24a, Sec24c, Sec24d, Sec23b, Sec31a, Sar1a, Sec61a1, Ssr3), suggesting a global decline in secretory activity
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