In addition to these widely used AOMs, Exenatide, one of the earliest GLP-1 RAs approved by the FDA and EMA for T2DM management, is not indicated for weight management but remains clinically relevant, particularly in older adults with comorbid obesity and T2DM, given its long-term clinical experience and established tolerability profile [26,27,28]
This variety is helpful, but it also means that the choice should be clinical and practical , not just based on news headlines or whats available at the pharmacy
Semaglutide, with its 7-day half-life and once-weekly dosing, represents the longest-acting formulation currently available [23]
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