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The increase in gastrointestinal problems has been well-documented, and the rise in low blood pressure and kidney stones is probably because GLP-1 patients could be somewhat fluid-depleted from not eating or drinking as much, said Dr Stephen ORahilly, co-director of the Institute of Metabolic Science at the University of Cambridge

However, these parameters derive entirely from animal studies, and optimal human administration strategies remain undefined

Taking it with certain foods, high-fat meals, or within 30 minutes of other medications can further reduce absorption and limit therapeutic benefit

If your situation fits these criteria, continue with careful monitoring

Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum