Common side effects (affecting more than 1 in 10 people) include: Nausea and vomiting : Often most pronounced in the first few weeks Diarrhoea or constipation : Gastrointestinal motility changes are expected Decreased appetite : This contributes to weight loss but may be uncomfortable Abdominal pain or discomfort Injection site reactions : Redness, itching, or swelling at the injection site To minimise gastrointestinal symptoms, patients should eat smaller, more frequent meals, avoid high-fat foods, and stay well hydrated
Theres no downtime
When patients show low GLP-1 persistence or discontinue their medications early, they dont achieve the weight loss needed to reduce their risk for cardiometabolic diseases, and payers face wasted spend and insufficient ROI
doi: 10.1016/j.cgh.2020.05.026 67
(PubMed) Lynch KE, Feldman HI, Berlin JA, Flory J, Rowan CG, Brunelli SM